The Pennsylvania Railroad ended up using the greatest number (598) of 2-10-0 locomotives. They were quite successfully used on the PRR Allegheny Mountain routes.
Because of the lack of a rear truck, the 2-10-0 wheel arrangement meant that the firebox be place between the drives making it very narrow or on top of the drivers making it very high and shallow also limiting the driver diameter. As a result, these locomotives could only be used for slow drag service.
| No. | Class | F.M. Whyte | Gauge | Railroad Line | Location | Status | Builder Info | Notes |
|---|---|---|---|---|---|---|---|---|
| 1615 | Russian | 2-10-0 | 4'-8½" | SLSF | Missile Park, Altus, OK | display | Baldwin #58829, 1917 | |
| 950 (600) | G | 2-10-0 | 4'-8½" | MSP&SSM (Buffalo & Susquehanna) | near depot, Ashland, WI | display | Baldwin #17914, 1900 | |
| 1632 | Russian | 2-10-0 | 4'-8½" | SLSF (Southern) | Belton Grandview & Kansas City Railroad, Belton, MO | cosmetic restoration | Baldwin #48522, 1918 | |
| 203 (402) | D-2 | 2-10-0 | 4'-8½" | GM (AT&N) | Southeastern Railway Museum, Duluth, GA | display | Baldwin #60342, 1928 | |
| 1625 | Russian | 2-10-0 | 4'-8½" | SLSF | Museum of the American Railroad, Frisco, TX | display | Alco (Schenectady) #58903, 1918 | |
| 209 (533) | D-2 | 2-10-0 | 4'-8½" | GM (SAL) | W Academy St, Gainesville, GA | display | Baldwin #61233, 1930 | |
| 4483 | I1sa | 2-10-0 | 4'-8½" | PRR | Western NY Railway Hist Soc, Hamburg, NY | display | Baldwin #56534, 1923 | Restoration candidate with the proper funding. May be moved to the Heritage Discovery Center. |
| 544 (206) | Russian | 2-10-0 | 4'-8½" | SAL (GM) | North Carolina Transportation Museum, Spencer, NC | display | Alco (Brooks) #58902, 1918 | |
| 1621 | Russian | 2-10-0 | 4'-8½" | SLSF | Museum of Transportation, St. Louis, MO | display | Baldwin #48420, 1918 | |
| 90 | BLWl | 2-10-0 | 4'-8½" | GWR | Strasburg Railroad, Strasburg, PA | operational | Baldwin #57812, 1924 | One of only two 2-10-0s in service |
| 41 (401) | BLWl | 2-10-0 | 4'-8½" | Woodward Iron (AT&N) | Age of Steam Roundhouse, Sugarcreek, OH | display | Baldwin #60341, 1928 | Sold to Georgia Car & Loco Co. in 1946; sold to Woodward Iron Co. in 1948; sold to Mid-Continent RR Museum in 1964 |
| 1630 | Russian | 2-10-0 | 4'-8½" | SLSF | Illinois Railway Museum, Union, IL | operational | Baldwin #47953, 1918 | Appeared in A League of Their Own |
| 208 (530) | D-2 | 2-10-0 | 4'-8½" | GM (SAL) | Winder Chamber of Commerce, Winder, GA | display | Baldwin #61230, 1930 |